July 7, 2004
BETHESDA, MD –
Adherence to
the traditional Mediterranean diet is associated with a
reduction in the concentrations of inflammation and
coagulation markers.
A study by
Christina Chrysohoou, MD, PhD et al. from University of Athens,
Athens, Greece which was published in the July 7, 2004 issue of
the Journal of American College of Cardiology, used data from
the ATTICA Study to evaluate the effect of the Mediterranean diet
on plasma levels of C-reactive protein, white blood cell counts,
interleuikin-6, tumor necrosis factor-alpha, amyloid A,
fibrinogen, and homocysteine. These levels are considered to be
markers of inflammation and coagulation.
In the ATTICA Study, during
the 2001 to 2002 period, 1,514 men and 1,528 women from the
Attica area of Greece were enrolled. These men and women covered
the age span of 18-89, and did not include people with a history
of cardiovascular disease. Participants were assessed on their
adherence to the Mediterranean diet, including daily consumption
of wine, whole-grains, vegetables, fruits, olive oil,
non-fat/low-fat dairy products, fish, poultry, potatoes, olives,
nuts, and less often consumption of eggs, sweets, and red meat.
The study found that
participants with the closest adherence to the traditional
Mediterranean diet had, on average, 20% lower C-reactive protein
levels, 14% lower white blood cell counts, 17% lower
interleukin-6 levels, 6% lower fibrinogen levels, and 15% lower
homocysteine levels compared to those adhered the least to the
Mediterranean diet.
From these
values, the study concluded that adherence to the traditional
Mediterranean diet is associated with a reduction in the
concentrations of inflammation and coagulation markers. The
authors believe that the low levels of these markers may
possibly explain why this diet is beneficial to the
cardiovascular system.
|